| Big Branch | rises in S Transylvania County and flows SW into East Fork French Broad River. |
| Big Branch | rises in E Transylvania County near Shuford Mountain and flows SW into Little Mountain. |
| Big Branch | rises in S Randolph County and flows SW into Little River. |
| Big Branch | rises in NE Swain County and flows SE into Enloe Creek. |
| Big Branch | rises in SW Nash County and flows SW into Turkey Creek. |
| Big Branch | rises in N Mitchell County and flows E into Right Fork Bean Creek. |
| Big Branch | rises in S Madison County and flows NE into Robert Branch. |
| Big Branch | rises in E Madison County and flows S into Little Ivy Creek. |
| Big Branch | rises in S Haywood County and flows NE into Little East Fork Pigeon River. |
| Big Branch | rises in N Macon County and flows NW into Cold Spring Creek. |