| Silvermine Branch | rises in NE Cherokee County and flows SE into Valley River. |
| Silvermine Branch | rises in N Madison County and flows SW into French Broad River. |
| Silvermine Branch | rises in central Swain County and flows SW into Lands Creek. |
| Silvermine Creek | rises in SW Swain County and flows NE into Nantahala River. |
| Silvermine Gap | SW Swain County on the head of Silvermine Creek. |
| Silvers Cove | E Haywood County on the head of Silvers Cove Creek. |
| Silvers Cove Creek | rises in E Haywood County in Silvers Cove and flows SW into Rush Fork. |
| Silverstone | community in N Watauga County on Sharp Creek. |
| Sim | community in E Robeson County served by post office, 1888-1903. |
| Simes Creek | See Perry Creek. |